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  1. eMagazine Horticulture
  2. Ciflufenamida, new molecule fungicida for the control of oídio in vegetables   (18/02/2013)

This news article was originally written in Spanish. It has been automatically translated for your convenience. Reasonable efforts have been made to provide an accurate translation, however, no automated translation is perfect nor is it intended to replace a human translator. The original article in Spanish can be viewed at Ciflufenamida, nueva molécula fungicida para el control de oídio en hortalizas
Elio is a formulated adapted for his employment in the Integrated cheese cheese Gestión of Plagues (GIP) and in the control of illnesses

Ciflufenamida, new molecule fungicida for the control of oídio in vegetables

Elio is a formulated to base of the new molecule ciflufenamida (NF 149), only representative of the chemical group of the fenil-acetamidas (amidoximas) with way of different action to the of other fungicidas with action antioídio existent, at present, in the market, with which does not present resistance crossed. Ciflufenamida Is an active matter, discovered and developed by Nippon Soda, for the control, mainly, of distinct species of oídio of numerous crops, in treatments so much preventive like curativos. The molecule acts inhibiting the learning of haustoriums, the growth of the micelio and the production of inoculum, showing high capacity to fix in the waxles of the cuticle of the leaves of the plants as well as a good activity translaminar, in phase steam, possessing a long persistence. The experimentation of both formulated, llevar in Spain and Italy, has showed an excellent efficiency for the control of oídio in the crops tested, comparable or upper to which show the best standards of the current market.
M. Ruiz García; J. Prades i Latorre; To. Ruiz-Jaén, and J.R. Soler Gil-Mascarell (Sipcam Iberia)
Ciflufenamida Is a new pertaining molecule to the new group fungicida of the amidoximas discovered and developed by the society Nippon Soda, included in the Annex I (Dir. 91/414 CEE) on 1 April 2010. It has been experienced and tuned for his employment in the conditions agroclimáticas south of Europe, as well as in numerous countries of the rest of the continent and the world, for the control of the oídio in diverse crops. It possesses an important action fungicida on funguses fitopatógenos of the family ‘Erysiphaceae', that includes the majority of the funguses causantes of the oídios, although they are not only these the only pathogens on which is active.

Elio controls effectively the illnesses caused mainly by the family ‘Erysiphaceae' to the doses authorised. It possesses preventive activity and curativa, with a good level of efficiency that, associated to an original and innovative way of action, does that ‘Elio' was a formulated adapted to be included in programs of control anti-resistances contributing to improve the protection of the crops. This turns it into a fungicida complete and sure. In this article document the characteristics of the new molecule and of the formulated, as well as a summary of the results of the experimentation llevar in Spain (2008-2010) and Italy (2007-2011) in vegetables. In base to the results of the studies toxicológicos and ecotoxicológicos effected with the active substance ciflufenamida and Elio, concludes that has a favourable profile, so much for the people and animal as for the environingingment.

Characteristics

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Table 1: physical Characteristics-chemical. Dangerousness for the people of Elio: Xn (Harmful).
Way of performance
Ciflufenamida Exerts an effective control on diverse funguses Ascomicetos, between which finds the family ‘Erysiphaceae', that includes the majority of the funguses causantes of the oídio, not being effective for the control of funguses Oomicetos. The activity fungicida, observed in vitro, confirms with the essays llevar in field during the last years in different crops, to which the oídio attacks with severity. The molecule, through his formulated, presents so much preventive activity like curativa and acts inhibiting the learning of haustoriums, the growth of the micelio and the learning of inoculum, in particular on ‘Blumeria graminis' f. sp. ‘tritici' (Of Candolle) And. Or., where has observed that it does not inhibit the germination of spores neither the learning of the apresorios, whereas yes it acts preventing the learning of haustoriums, the growth of the micelio and the production of inoculum. In cucumber, as in other crops, has observed his penetrating activity with mobility especially translaminar in phase steam (although with low pressesure of steam) and with long persistence.
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It appears 1: Action of ciflufenamida on the growth of the micelio of the fungus Uncinula necator (Schwein Burrill). Oídio Of the vineyard.
In the Figure 1 can see two photos realised with electronic microscope of scanning (SEM) in which they observe the apexes hifales of Uncinula necator in leaves of vineyard treated and no treated with ciflufenamida. It observes the absence of turgencia and the apparition of a vesicle in the apex hifal treaty, what indicates a possible effect degenerativo of the cellular walls of the same.
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Chart 1: Activity translaminar of ciflufenamida for the control of 'Podosphaera fusca' (Fries) Braun et., in leaves of cucumber (inoculation 10 days after the application).
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Chart 2: Activity in phase steam of ciflufenamida for the control of ‘Podosphaera fusca' (Fries) Braun et., in leaves of cucumber (inoculation 10 days after the application).
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Chart 3: Persistence of ciflufenamida for the control of 'Podosphaera fusca' (Fries) Braun et. In cucumber, 10 days afterwards his application.
Way of action
The way of action of ciflufenamida is still unknown, the Fungicide Resistance Action Comittee (TAILCOAT) includes it, in his classification, as only representative of a new chemical group of fungicidas.
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Table 2: Classification TAILCOAT (update 2012). Way of action, Chemical Group and Code.
This committee (TAILCOAT) recommends the use of ciflufenamida inside strategies of control adapted, to avoid or minimise the apparition of resistances, respecting for this the conditions and way of employment that collect in the labels of the formulated.

Does not present resistance crossed with other fungicidas antioidios of the chemical groups of the triazoles, estrobirulinas, benzimidazoles, morfolinas and with active matters like Quinoxifen (quinolinas), Bupirimato (aminopirimidinas) or Boscalida (carboxamidas).

Spectrum of action

Elio is a formulated with excellent preventive effect and curativo on funguses of the family of ‘Erysiphaceae' where include diverse responsible genders of the illness of the oídio in horticultural.
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Table 3: Permissions of formulated of ciflufenamida in other European countries for the control of oídio in distinct crops.
In the Table 4 relate the uses for which Sipcam has requested the register of Elio in Spain indicating the doses, the number of applications as well as the interval between the same and the terms of hygiene.
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Table 4: Uses requested in Spain of Elio (ciflufenamida 10% p/v (100 g/l) SC).

Experimentation and development in Spain and Italy

The results that here collect have obtained in essays llevar in Spain and Italy during the years 2008 and 2011. During these years of experimentation and development, Elio has showed an optimum activity for the control of the oídio in vegetables, and other crops showing his preventive performance and curativa, beside a good level of efficiency.
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Chart 4: Efficiency of Elio for the control of oídio (‘Podosphaera fusca' (Fries) Braun et Shishkoff) in cucumber in invernadero. (Plan of Essays 2008-2011 Sipcam).
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Chart 5: Efficiency of Elio for the control of oídio (‘Podosphaera fusca' (Fries) Braun et Shishkoff) in melon in the open air. (Plan of Essays 2008-2011 Sipcam). (Interval of treatments: To-7 and B-14 days).
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Chart 6: Efficiency of Elio for the control of oídio (‘Podosphaera fusca' (Fries) Braun et Shishkoff) in pepper in invernadero. (Plan of Essays 2008-2011 Sipcam).

Conclusions

Ciflufenamida Is a new molecule fungicida, with a high control on the illnesses caused by the family of ‘Erysiphaceae' (oídios), is penetrating, high sample capacity to fix in the waxles of the cuticle, with mobility translaminar in phase steam and possesses a long persistence.

His performance is preventive and curativa, with a good level of efficiency that, associated to an original and innovative way of action (new chemical group Or6), does that Elio was especially adapted to be included inside strategies that avoid the apparition of resistances and improve the hygiene of protection of the crops. In base to the results of the studies toxicológicos and ecotoxicológicos effected with said active substance and the formulated, concludes that his profile toxi and echo-toxicológico does not represent any risk for the users, consumers and terrestrial fauna, as well as for the microorganisms of the floor, bees, abejorros pollinators and other beneficial organisms (OCB).

Ésto Does that Elio was a formulated adapted for his employment in the Integrated cheese cheese Gestión of Plagues (GIP) and in the control of illnesses, such as it establishes the Directive of Sustainable Use of the Phytosanitary ware (D 2009/128 CE) and, also, by his respect to the useful and beneficial arthropods. Besides it is necessary resaltar his low term of hygiene and the availability of LMR harmonised for all Europe in the crops authorised (and in roads of permission).
Bibliographic references

- Cortesi P., Querzola P., Capella To., Rubboli V., Serrati To., Myrta To., 2012. Cyflufenamid: nuova molecola fungicida per il contenimento dell'oidio della vite, of the melo and gave cucurbitacee and solanacee. Atti Giornate Fitopatologiche, 2, 195-200.

- Capriotti M., Querzola P., Bellotto D., Guastamacchia F., Capella To., 2012. Verifiche sperimentali sull'oidio della vite And of the melo with Rebel, fungicida to base gave cyflufenamid. Atti Giornate Fitopatologiche, 2, 333-338.

- Haramoto M., Yamanaka H., Kosokawa H., Healthy H., Healthy S., Otani H., 2006 to. Sensitivity monitoring of powdery mildew pathogens you cyflufenamid and the evaluation of resistance risk. J. Pestic. Sci., 31 (4), 397-404.

- Haramoto M., Yamanaka H., Kosokawa H., Healthy H., Healthy S., Otani H., 2006 b. Control efficacy of Cyflufenamid in the field and its fungicidal properties. J. Pestic. Sci., 31 (2), 116-122.

- Haramoto M., Yamanaka H., Kosokawa H., Healthy H., Healthy S., Otani H., 2006 c. Fungicidal activities of cyflufenamid against various plant-pathogenic fungi. J. Pestic. Sci., 31 (2), 95-101.

- Healthy S., Kasahara I., Yamanaka H., 2007. Development of To novel fungicide, cyflufenamid. J. Pestic. Sci., 32(2), 137-138.

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